Epson's micropiezo technology produces outstanding photos, but is prone to clog particularly when the printer is not used frequently.
Prevention seems to be the key:
-don't refill the cartridges
-don't buy generics
-use the printer frequently
If you do refill a cartridge, let it sit overnight to allow time for the ink to absorb into the sponge and for bubbles to dissipate.
Despite the best of efforts, you may still suffer clogging problems. Some suggestions for solutions to this problem have included:
-repeated head cleanings
-using cleaning cartridges
-Isopropyl alcohol treatments
Some instruction/product links that have been useful to Dealmac forum readers: